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National Kidney Foundation

National Kidney Foundation

Find Out What Drugs Can Be Dangerous for CKD Patients

Find Out What Drugs Can Be Dangerous for CKD Patients

Discover common medications and substances that can be harmful to your kidneys and should be taken under doctor supervision or be avoided altogether.


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Did you know certain drugs and substances can damage your kidneys? It is important for people with chronic kidney disease (CKD) to talk to their doctors before taking any drugs, including over-the-counter (OTC) medications. Learn more about specific drugs and substances that can be harmful to CKD patients

Pain Medications

Taking OTC pain medications regularly for too long can damage your kidneys. Aspirin, naproxen, and ibuprofen should not be taken daily or regularly without first talking to your doctor. 

Antibiotics

Excessive intake of antibiotics can be dangerous to CKD patients. Take only antibiotic medications ordered for you by your healthcare provider. Be sure to call your doctor if you’re experiencing any alarming or unusual symptoms. 

Prescription Laxatives

In general, OTC laxatives are safe for CKD patients. However, some prescription laxatives used to clean the bowel can be harmful to the kidneys. 

Contrast Dye

Used in imaging tests, such as MRIs, and CT scans, contrast dye may be given to a patient and help produce better imaging results. For those with CKD, however, contrast dyes can be harmful. Not all imaging tests require or need dyes to be effective. Talk to your doctor about your concerns and to assess your risk. 

Alcohol and Illegal Drugs

Alcohol and street drugs (heroin, cocaine, ecstasy) can negatively affect multiple areas of your body, including your kidneys, liver, and heart. If you or a loved one have alcohol or drug addictions, speak to your doctor about resources to help.  

What Are Some Helpful Tips?

Here are a few ways to stay healthy and avoid illness from medications and substances:

  • Avoid taking any medicine, drug, or substance unless you are under a healthcare provider’s guidance.
  • Do not take pills given to you by a stranger or friend (even a family member who claims they have the same type of medicine that you need or were prescribed). 
  • If you feel ill after taking any medication or substance, contact your healthcare provider immediately.
  • If you need to have an imaging test or colonoscopy, be sure to let your healthcare provider know if you have CKD or are at risk of getting it. 

*Which Drugs are Harmful to Your Kidneys? (2021, December 3). National Kidney Foundation. https://www.kidney.org/atoz/content/drugs-your-kidneys

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