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American Kidney Fund

American Kidney Fund

Understanding Diuretics for Kidney Disease

Understanding Diuretics for Kidney Disease

Learn why your doctor may prescribe diuretics when you have chronic kidney disease.


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If your doctor has mentioned “water pills” or diuretics, you might be wondering what they are and how they help. These medications play a key role in managing conditions like high blood pressure, kidney disease, and heart failure by helping your body get rid of extra salt and fluid. Let’s break it down in plain language so it’s easier to understand what these meds do and why they matter.

Why Diuretics Matter for Your Kidneys and Blood Pressure

When your kidneys aren’t working as well as they should, your body tends to hold on to extra fluid and salt. That added fluid increases your blood pressure, which can further damage the kidneys—kind of like a domino effect. Diuretics interrupt this cycle by helping your kidneys flush out excess salt and water through your urine. This reduces the pressure in your blood vessels and gives your kidneys a break.

There are three main types of diuretics, each working a bit differently:

Things to Watch Out For

Diuretics are generally safe but can have side effects. The most common ones include:

  • More frequent urination,
  • Dizziness or lightheadedness, and
  • Muscle cramps or weakness from low potassium.

Like any medication, there may be some serious potential side effects for people:

  • With certain allergies, 
  • Who are breastfeeding, pregnant, or trying to get pregnant, and 
  • Who have other medical conditions or who are taking certain other medications.

If you’re taking diuretics, it’s a good idea to stay in close touch with your healthcare provider. They can help you decide which diuretics are best for you, manage any side effects, and make sure the medication is doing its job without causing new problems.

*American Kidney Fund. (2024, March 11). Diuretics. https://www.kidneyfund.org/treatments/medicines-kidney-disease/diuretics#:~

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