Living with chronic kidney disease (CKD) often means managing more than just your kidney health. You may also find yourself coping with persistent fatigue that affects your daily life. From the physical strain of anemia to the emotional toll of ongoing stress, fatigue in CKD can be complex and multifaceted. The good news is that there are practical, science-backed ways to regain your energy and improve your well-being.*

Why CKD Makes You Feel Tired All the Time

Fatigue is one of the most common, and frustrating, symptoms of CKD. Even if you’re getting plenty of rest, you may still feel worn out. That’s because CKD impacts your body on several levels. One major culprit is anemia, caused by the kidneys’ reduced ability to produce erythropoietin, a hormone that stimulates the production of red blood cells. Fewer red blood cells mean less oxygen circulating in your body, leading to that drained, sluggish feeling.

But anemia isn’t the only factor. CKD also brings about: 

• Changes in blood chemistry and metabolism, 
• Loss of muscle mass, 
• Nutrient deficiencies, and 
• Chronic inflammation.

All of these can contribute to ongoing fatigue. In addition, medications and comorbid conditions like diabetes, heart disease, anxiety, and/or depression can exacerbate your symptoms.

Small Lifestyle Tweaks That Can Make a Big Difference

Managing your fatigue starts with creating a lifestyle that supports your energy needs. 

• Sleep. Prioritize good sleep hygiene and aim for at least 7 hours each night. Keep your bedroom electronics-free, and stick to a consistent bedtime. If you’re still tired during the day, talk with your doctor about potential sleep disorders.
• Exercise. Exercise might sound counterintuitive when you’re exhausted, but moving your body actually helps. Even moderate activity like brisk walking or water aerobics can improve your stamina, mood, and overall health. Talk to your doctor or a physical therapist before starting something new.
• Stress management. Stress can be both a cause and a result of fatigue. Find outlets that work for you—whether that’s deep breathing, spending time with friends, or journaling. Managing stress is just as important as managing your lab numbers.
• Energy conservation. This is also key. Learn to “budget” your energy by prioritizing your most demanding tasks for when you feel most awake, taking regular breaks, and saying no to activities that drain you unnecessarily.

Food, Fluids, and Mental Fuel

Nutrition and hydration play an essential role in your energy levels. Make sure you’re getting enough iron and B vitamins—nutrients vital for red blood cell production. If your doctor suspects a deficiency, they may suggest blood tests and supplements. Don’t take anything without their guidance, as some supplements can harm your kidneys.

Your ideal diet depends on your stage of CKD and other health conditions. In general, a balanced plate of fruits, vegetables, whole grains, and lean proteins can help you feel stronger. A renal dietitian can help tailor your eating plan, including how much protein, potassium, or sodium you should consume.

Lastly, don’t forget that emotional health matters. CKD can be isolating, and fatigue can worsen feelings of anxiety or depression. Talking to loved ones, joining a support group, or seeing a mental health professional can help lighten the emotional load and renew your sense of control.

Managing fatigue with CKD isn’t just about treating one symptom—it’s about creating a supportive, holistic plan that addresses your body, mind, and everyday habits. With the right strategies and medical support, you can reclaim your energy and improve your quality of life.

*Grey, H. (2024, November 15). Managing Fatigue with Chronic Kidney Disease. Healthline.

https://www.healthline.com/health/kidney-disease/managing-fatigue-from-ckd 

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